Savaş Selçuk, Nihat Zalluhoğlu, Alp Gürkan, Serdar Kaçar, Selçuk Kılıç, Cezmi Karaca, Can Varılsüha

SSK Tepecik Eğitim Hastanesi 3. Cerrahi Kliniği, İZMİR



Materials and Methods: From 1995 to 2003, 42 patients who underwent surgery due to infiltrative ductal carcinoma without lymph node metastasis were included in the study. 25 (59.5%) of these patients were treated with modified radical mastectomy (MRM), while 17 (40.5%) were subjected to breast conserving (BC) surgery. All patients with BC surgery received radiotherapy and all patients with T2 and T3 tumors received antracycline based adjuvant chemotherapy. Based on their estrogen receptor status, they were also given tamoxifen. Patients had follow-ups every three months in the first year of post-operation and every six months thereafter.

Results: Both groups of patients had periodic follow-ups over the course of the study (6 - 1005 months). Both groups were similar in terms of age, tumor localization, menopausal status and number of dissected lymph nodes. One (5.8%) of the patients in BC group had local recurrence and was treated with mastectomy. Another patient had lung and liver metastases in the 80th month. In the MRM group 4 (16%) patients had contra-lateral breast cancer between 6 and 24 months, postoperatively. None of the patients died in the both groups.

Conclusion: In early stage of breast cancer, BC surgery was found to be as safe as MRM in terms of its post-operative disease-free nature and its total survival rate.

Keywords: Breast conserving surgery, breast cancer, modified radical mastectomy