Wafi Attaallah1, Şafak Coşkun1, Gülden Özden1, Hande Mollamemişoğlu2, Cumhur Yeğen1

1Department of General Surgery, Marmara University Faculty of Medicine, İstanbul, Turkey
2Department of Pathology, Marmara University Faculty of Medicine, İstanbul, Turkey


Tumor perforation is accepted as an important prognostic factor along with tumor size and mitotic index in gastrointestinal stromal tumors (GIST). The prognosis is worse in patients with tumor perforation or rupture. A few case reports of small bowel GIST presenting with rupture have been published in the medical literature. We report an unusual case of a 7.5 cm GIST of the jejunum that presented with spontaneous rupture. A previously healthy 46-year-old male patient presented with sudden abdominal pain. Physical examination revealed overt peritonitis, and computed tomography showed a heterogeneous solid mass measuring approximately 6 cm x 5.5 cm arising from the jejunum and massive fluid in the peritoneum. The mass was diagnosed as a GIST originating from the gastrointestinal tract. Emergency laparotomy was performed and intraoperative findings showed massive hemoperitoneum and an outgrowing mass at the jejunum, 50 cm distal to the Treitz ligament. The tumor had ruptured near the wall of the small intestine and it was actively bleeding. Surgical resection of the tumor was performed and the patient was discharged home uneventfully on the third postoperative day. The immunohistochemical characteristics of the tumor revealed it to be a GIST.

Keywords: Gastrointestinal stromal tumor, rupture, acute abdomen, hemoperitoneum


Peer Review

Externally peer-reviewed.

Author Contributions

Concept - W.A., Ş.C., G.Ö.; Design - C.Y.; Supervision - W.A., H.M.; Funding - G.Ö., H.M.; Materials - Ş.C., W.A.; Data Collection and/or Processing - C.Y.; Analysis and/or Interpretation - H.M.; Literature Review - W.A.; Writer - W.A.; Critical Review - G.Ö., C.Y.

Conflict of Interest

No conflict of interest was declared by the authors.

Financial Disclosure

The authors declared that this study has received no financial support.