Hamdi Burak Piyade1, Mahmut Başoğlu2, Ersan Gürsoy3

1Clinic of General Surgery, Gümüşhane State Hospital, Gümüşhane, Türkiye
2Department of General Surgery, Ondokuz Mayıs University Faculty of Medicine, Samsun, Türkiye
3Department of Family Medicine, Binali Yıldırım University Faculty of Medicine, Erzincan, Türkiye


Objective: Thyroid gland surgery and its surgical complications are situations that a surgeon frequently encounters in his daily practice. In our study, it was aimed to examine the effect of different treatment methods given to patients who underwent thyroidectomy on hypocalcemia.

Material and Methods: Three hundred and seventy-one patients who underwent thyroidectomy at Ondokuz Mayıs University Medical Faculty General Surgery clinic between December 2016 and January 2021 were retrospectively included in the study. Parameters such as surgery indications, fine needle aspiration biopsy results, preoperative serum calcium values, type of surgery, serum calcium values at postoperative 1st day and 1st month, postoperative hospital stay, drugs prescribed at discharge, histopathological diagnosis of the patient, and whether there was incidental parathyroidectomy or not were included.

Results: Mean age of 371 patients who underwent thyroidectomy was 49 (19-82) years. Total thyroidectomy was the most common type of thyroidectomy with 61% (n= 225) of the patients. There was a significant decrease in pre-op and post-op calcium values in all three types of surgery performed on the patients, and there was no significant difference between the different types of surgery. Post-operative day one and month one serum calcium values were significantly increased in all groups (p= .000). The increase in post-op serum calcium level was most common in the group using calcium carbonate + cholecalciferol + calcitriol.

Conclusion: The use of post-op calcitriol in patients undergoing thyroidectomy seems to be quite effective in preventing the development of hypocalcemia.

Keywords: Thyroidectomy, hypocalcemia, calcitriol, thyroid diseases

Cite this article as: Piyade HB, Başoğlu M, Gürsoy E. The effect of different therapeutic treatments on the frequency of postoperative hypocalcemia in patients with thyroidectomy. Turk J Surg 2023; 39 (1): 70-75.


Ethics Committee Approval

This study was approved by Ondokuz Mayıs University Clinical Research Ethics Committee (Decision no: OMÜ KAEK 2020/416, Date: 27.08.2020).

Peer Review

Externally peer-reviewed.

Author Contributions

Concept - All of authors; Design - All of authors; Supervision - All of authors; Fundings - All of authors; Materials - All of authors; Data Collection and/ or Processing - All of authors; Analysis and/or Interpretation - All of authors; Literature Search - All of authors; Writing Manuscript - All of authors; Critical Reviews - All of authors.

Conflict of Interest

The authors have no conflicts of interest to declare.

Financial Disclosure

The authors declared that this study has received no financial support.