Metin Yücel, Muhammed Taha Demirpolat, Muhammed Kadir Yıldırak

Clinic of General Surgery, Ümraniye Training and Research Hospital, İstanbul, Türkiye


Objective: Screening programs are important for the early detection of colorectal cancer, which is one of the causes of high morbidity and mortality. In this study, we investigated the colonoscopy results, the incidence of adenoma and cancer, and the relationship between test results and cancer in individuals with a positive fecal occult blood test for colorectal cancer screening.

Material and Methods: Within the scope of the colorectal cancer screening program, colonoscopy was requested for individuals aged 50-70 years who applied to our outpatient clinic with a positive fecal occult blood test. The results were collected and analyzed.

Results: The results of the colonoscopy could be obtained in only 237 (56.43%) of the 420 patients who were referred for a colonoscopy because of a positive fecal occult blood test. Colonoscopy results were normal in 15 (6.33%), benign anal disease in 64 (27%), benign colonic disease in 12 (5.06%) and polyp + adenocarcinoma in 146 (61.61%). Pathology results were benign polyp in 37 (15.61%), adenomatous polyp in 86 (36.29%) and adenocarcinoma in 23 (9.71%). Quantitative test results were higher in the adenomatous polyp + adenocarcinoma group and statistically significant (p= 0.03).

Conclusion: Individuals with positive fecal occult blood tests, especially those with high quantitative test results, should be encouraged to have a colonoscopy, and they should be warned about the high probability of adenomatous polyps and colorectal cancer.

Keywords: Colorectal cancer screening, fecal occult blood test, immunochemical test, colonoscopy

Cite this article as: Yücel M, Demirpolat MT, Yıldırak MK. Colorectal cancer screening; colonoscopy and biopsy results in people undergoing colonoscopy due to positive fecal occult blood test. Turk J Surg 2024; 40 (1): 59-64.


Ethics Committee Approval

This study was approved by Ümraniye Training and Research Hospital Clinical Research Ethics Committee (Date: 28.06.2019, Decision no: 12832).

Peer Review

Externally peer-reviewed.

Author Contributions

Concept - MY; Design - All of authors; Supervision - MTD, MKY; Materials - All of authors; Data Collection and/or Processing - MY; Analysis and/or Interpretation - All of authors; Literature Review - MY; Writer - MY, MTD; Critical Review - MTD, MKY

Conflict of Interest

The authors have no conflicts of interest to declare.

Financial Disclosure

The authors declared that this study has received no financial support.