Primary neuroendocrine tumor of the perihilar bile duct: A case report
Mustafa Salış1
, Muhammed Kandemir2, Elif Gündoğdu3, İlter Özer4, Bülent Ünal5, Murat Ulaş6
1Clinic of General Surgery, University of Health Sciences, Eskişehir City Health Practice and Research Center, Eskişehir, Türkiye
2Clinic of General Surgery, Cizre Dr. Selahattin Cizrelioğlu State Hospital, Şırnak, Türkiye
3Department of Radiology, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir, Türkiye
4Clinic of Gastrointestinal Surgery, Private Clinic, Ankara, Türkiye
5Department of General Surgery, İstanbul Aydın University Faculty of Medicine, İstanbul, Türkiye
6Department of General Surgery, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir, Türkiye
Abstract
Neuroendocrine tumors (NETs) arising from extrahepatic bile ducts are very rare. We present a patient with perihilar NET who was operated on with a preoperative diagnosis of Klatskin tumor. A 58-year-old female patient was admitted with abdominal pain and jaundice. Laboratory data showed elevated serum bilirubin levels and liver function tests. Computed tomography (CT) and magnetic resonance cholangiopancreatography (MRCP) findings were consistent with perihilar bile duct tumor. The patient was operated on with a diagnosis of Klatskin tumor. She underwent right hepatectomy, resection of the extrahepatic bile duct, portal lymphadenectomy and Roux-en-Y hepaticojejunostomy. The final pathologic examination of the resected specimen demonstrated a well differentiated neuroendocrine tumor (Grade 1). NETs originating from perihilar bile ducts are extremely rare, and preoperative definite diagnosis is very difficult. It should be kept in mind that NET may be one of the rare causes of perihilar bile duct obstruction.
Keywords: Neuroendocrine tumor, perihilar bile duct, resection
Cite this article as: Salış M, Kandemir M, Gündoğdu E, Özer İ, Ünal B, Ulaş M. Primary neuroendocrine tumor of the perihilar bile duct: A case report. Turk J Surg 2024; 40 (3): 261-263.
Informed consent was obtained from patient who participated in this case.
Externally peer-reviewed.
Concept - İÖ, MS, BÜ, EG; Design - MS, MK, İÖ, EG; Supervision - İÖ, BÜ, MU; Materials - MS, MK, EG; Data Collection and/or Processing - MS, EG, MU; Analysis and/or Interpretation - MS, İÖ, BÜ, MU; Literature Search - MS, İÖ, EG; Writing Manuscript - MS, İÖ, EG; Critical Reviews - İÖ, BÜ, MU.
The authors have no conflicts of interest to declare.
The authors declared that this study has received no financial support.