DUCTAL CARCINOMA IN SITU : A RETROSPECTIVE STUDY

Abstract

In this study the clinical and pathological properties as well as treatment modalities and outcomes of the patients diagnosed as isolated ductal carcinoma in situ in our clinic is presented. Ductal carcinoma in situ has become an easily recognized lesion owing to the recent developments in imaging techniques and widespread use of mammography and needle guided breast biopsy, consisting 25% of all breast cancers. 16 patients diagnosed as ductal carcinoma in situ between January 1986 and December 1996 are retrospectively studied in terms of age, symptoms, physical examination findings,mammographical and ultrasound findings, surgical and adjunctive treatments and follow up. All patients were women, between age of 30 and 65 (mean 43).Needle guided breast biopsy was done in 11 patients who had mammographic lesion on their screening mammography. Surgical treatments were modified radical mastectomy in 7 cases, wide excision and axillary dissection with radiotherapy in 3 cases and wide excision only in 6 cases. Local recurrence and distant metastasis was not observed in patients treated with modified radical mastectomy during 7-77 (mean 44) months follow up. Wide excision with radiotherapy group during 23-51 (mean 39) months follow up and wide excision during 6-38 (mean 27) months follow up had no recurrence or metastasis also. We concluded that a standardized treatment of ductal carcinoma in situ should be developed instead of individual treatment choices since the number of in situ ductal carcinoma cases has been increasing.