EFFECT OF PREOPERATIVE INHIBITION OF PROSTAGLANDIN SYNTHESIS ON POSTOPERATIVE PAIN AND ANALGESIC NEED IN INGUINAL HERNIA OPERATIONS
İSHAK ÖZAÇMAK, FERDA KÖKSOY, HAKKI KÖSE, GÜRSEL SOYBİR, YALÇIN AKER, MUSTAFA BALOĞLU
İstanbul Taksim Hastanesi, 1.Cerrahi Kliniği, İSTANBUL
Abstract
In our study preoperative inhibition of prostaglandin synthesis by Tenoxicam in inguinal hernia operations was evaluated and compared with placebo in preventing postoperative pain.
Both Tenoxicam and placebo groups consisted of 20 patients each. Injection of Tenoxicam was given to the Tenoxicam group 2 hours before the operation. During the first 24 hours postoperative pain scores and analgesic drug need was evaluated by visual analog scala (VAS).
Statistical analysis revealed significant differences in mean VAS scores (p<0.01), Vas scores in hours, postoperative Metamizol injection need (p<0.001) of the two groups. Postoperative hospital stay, and incidence of side effects were not different significantly.
Keywords: PREEMPTIVE ANALGESIA, POSTOPERATIVE PAIN, INGUINAL HERNIA, TENOXICAM