THE EFFECT OF VASCULARY OCCLUSION PERIOD ON LIVER FUNCTION TESTS IN HEPATIC RESECTIONS

Abstract

The most important complication of hepatic resection is hemorrhage. That is why there are many techniques desribed by many authors. Portal triad occlusion is an alternative technique in hepatic resection in order to avoid hemorrhage. In normal individuals 60 minutes of ischemia can be tolerated by the liver without any functional damage. This study, 41 hepatic resections which were performed in the Surgical Oncology Department of Ankara University, Faculty of Medicine, between October 1991 and January 1994.

41 patients were the material of this study, 8 were cirrhotic and 33 were non-cirrhotic. In the non-cirrhotic group 24 patients were underwent hepatic resection with portal triad occlusion and 8 were without portal triad occlusion. In both groups liver function tests were elevated after surgery, but there was no significant difference (p>0.05). On postoperative seventh day SGOT and SGPT were reversed to normal values. 8 cirrhotic patients underwent hepatic resection with portal triad occlusion. The liver function tests of this group compared with the noncirrhotic ones, and no significant difference (p>0.05) was found.

In conclusion, portal triad occlusion can be tolerated for 60 mins in normal individuals and 30 mins in cirrhotic patients. The hepatic damage was monitorized by liver function tests and showed us that portal triad occlusion and ischemia did not cause more damage than the hepatic resection without portal triad occlusion. So portal triad occlusion is a well tolerated and reasonable alternative to avoid hemorrhage.