THE VALUE OF HEPATIC ARTERIAL INFUSION CHEMOTHERAPY IN THE PALLIATIVE TREATMENT OF LIVER TUMOURS
SUHA ÇAKMAKLI, MUAMMER KARAAYVAZ, EROL AKSAZ, ALİ RIZA ARAT, ABDÜLMUTTALİP ÜNAL
Ankara Üniversitesi Tıp Fakültesi, Cerrahi Onkoloji Bilim Dalı, ANKARA
The efficacies of hepatic arterial infusion chemotherapy in the treatment of liver tumors were evaluated in 32 patients. A complete response was seen in three patients, a partial response in five, a minor response in four, and a stable disease in eight and a progressive disease in 12 patients. The response rate was 62.5% and estimated survival was 12.84 ± 2.01 months. The treatment was seen more efficient in patients with less than 50% liver involvement. Fatal toxicities were not seen in any of the patients. In only 7.3% of all cycles, Grade HI toxicities were developed. Hepatic arterial infusion chemotherapy had demonstrated a successful palliation in patients with unrespectable liver carcinoma.
Keywords: LIVER TUMOURS, INTRA-ARTERIAL CHEMOTHERAPY