WHIPPLE OPERATION FOR THE TUMORS OF THE HEAD OF THE PANCREAS AND AMPULLARY REGION
KORAY SADIK ACARLI, AIİ EMRE, AYDIN ALPER, ORHAN ARIOĞUL, ŞÜKRÜ EMRE
İstanbul Üniversitesi, İstanbul Tıp Fakültesi Karaciğer Safra Yolları Cerrahisi Birimi/İSTANBUL
Abstract
Between 1977 and 1990, 25 patients had a Whipple resection for adenocarcinoma of the head of the pancreas (n:15) and ampulla (n:10). 20 patients were men, 5 were women, and the mean age was 48 years (range: 28-70 years). The patients were divided into two groups on the basis of two different time periods : those operated on from 1977 to 1985 (n:13) and those operated on from 1986 to 1990 (n:12). There were no significant differences between the two groups in terms of laboratory data. Among the 13 patients operated on during the first period, hospital morbidity and mortality rates were 58.4% and 46.2%, respectively. In contrast, hospital morbidity and mortality rates were 26.1% and 0%, respectively, among the 12 patients operated on during the second period. Because of decreasing morbidity and mortality rates, Whipple operation can be performed safely in curative treatment and paliation of pancreatic cancer.