THE EFFECT OF LAPAROSCOPIC CHOLECYSTECTOMY ON PLATELET AGGREGATION
Dr. Serdar YOL1, Dr. Adil KARTAL1, Dr. Şakir TAVLI1, Dr. Ümran ÇALIŞKAN1, Dr. Lütfiye PİRBUDAK2, Dr. Yüksel TATKAN1
1 Çocuk Sağlığı ve Hastalıkları ABD, KONYA
2Selçuk Üniversitesi Tıp Faklütesi, Genel Cerrahi ABD, Anesteziyoloji ve Reanimasyon ABD, KONYA
There has been no report about the effect of laparoscopy on platelet (PLT) aggregation. We operated on forty female patients with symptomatic gallbladder stone, twenty of them (study group) had laparoscopic cholecystectomy and twenty of them (control group), open cholecystectomy. The patients who have history of bleeding, abnormal PLT count, systemic disorders and those who are on salisilat, heparin, oral anticoagulant, etc., were excluded. Blood parameters have been checked at the beginning and at the end of the operation including PLT aggregation by using ADP, collagen and ristocetin in whole blood aggregometer. PLT aggregation was evaluated by "% Aggregation". PLT aggregation by collagen and ristocetin increased significantly at the end of the operation In the study group (p<0.002). Aggregation by ADP did not differ significantly. Control group results did not show any differences. In conclusion, although no clinical finding of aggregated PLT is observed in practice, we can explain that laparoscopy increases PLT aggregation.
Keywords: Platelet aggregation, stasis, intra-abdominal pressure, laparoscopy