A case report of peritoneal carcinomatosis of colorectal cancer treated with cytoreduction and hyperthermic intraperitoneal chemotherapy, and an overview of related medical literature
Cem Terzi1, Uğur Yılmaz2, Can Yakut1, Mücahit Özbilgin1, Funda Obuz3, Sülen Sarıoğlu4, Mehmet Füzün1
1Dokuz Eylül Üniversitesi Tıp Fakültesi Genel Cerrahi AD, İZMİR
2Dokuz Eylül Üniversitesi Tıp Fakültesi İç Hastalıkları AD, Medikal Onkoloji Bilim Dalı, İZMİR
3Dokuz Eylül Üniversitesi Tıp Fakültesi Radyoloji AD, İZMİR
4Dokuz Eylül Üniversitesi Tıp Fakültesi Patoloji AD, İZMİR
Abstract
The peritoneum is one of the most frequent site of the metastasis of colorectal cancer. Until recently, treatment of peritoneal carcinomatosis has been limited to palliative surgery and systemic chemotherapy with a median survival 4-12 months. But, cytoreductive surgery (including peritonectomies) and hyperthermic intraperitoneal chemothereapy has resulted in an unprecedented median survival > 20 months. The use of hyperthermia as an adjunct to chemotherapy in the treatment of peritoneal carcinomatosis of colorectal cancer is a new and very promising technique. We, herein, report of the first case of Turkey who had cytoreductive surgery and hyperthermic intraperitoneal chemothereapy with the diagnosis of peritoneal carcinomatosis of colon cancer. We also present the description of technique of hyperthermic intraperitoneal chemothereapy and an overview of the releted medical literature.
Keywords: Peritoneal carcinomatosis, colorectal cancer, hyperthermic intraperitoneal chemotherapy