Efficacy of clinoptilolite on hepatic parenchymal bleeding
Erhan Ayşan1, Hasan Bektaş1, Arslan Kaygusuz1, Gülben Erdem Huq2
1İstanbul Eğitim ve Araştırma Hastanesi Genel Cerrahi AD., İstanbul
2İstanbul Eğitim ve Araştırma Hastanesi Patoloji AD., İstanbul
Abstract
Purpose: Hepatic bleeding following abdominal trauma and hepatic surgery is a serious problem. Aim of this research is to evaluate of clinoptilolite on hepatic parenchymal bleeding.
Materials and Methods: Hepatic resection model was performed on 20 Wistar albino female rats. The efficacy of hemostasis with clinoptilolite has been evaluated through the comparison of perioperative bleeding amount and preoperative and postoperative hematocrit levels.
Results: Peroperative bleeding amounts were 0.3ml (0.18-0.4) in the control group, 0.2ml (0.1-0.3) in the clinoptilolite group (p>0.05). Preoperative and postoperative hematocrit differences were 9 (4- 12.3) in control group and 8 (4.75-10.5) in clinoptilolite group (p>0.05).
Conclusions: Clinoptilolite decreases peroperative and postoperative hepatic parenchymal bleeding, but is not statistically significant. Clinoptilolite is not effective on hepatic parenchymal bleeding.
Keywords: Hepatic, parenchyma, bleeding, clinoptilolite, prevention