Metastatic neuroendocrine tumor: The only liver transplant indication in metastatic tumors
Onur Yaprak, Kadir Koray Baş, Yıldıray Yüzer, Yaman Tokat
Florence Nightingale Hastanesi, Hepatobiliyer Cerrahi ve Organ Nakil Merkezi, İstanbul, Türkiye
Abstract
Neuroendocrine tumors are a heterogeneous group of neoplasms originating from endocrine cells, which are characterized by the presence of secretory granules as well as the ability to produce biogenic amines and polypeptide hormones. They are characterized by slow growth and frequent metastasis to the liver. The therapeutic approach to hepatic metastases should be considered with the number and distribution of the liver metastases. Liver transplantation should be considered in patients with neuroendocrine metastases to the liver that are not accessible with curative or cytoreductive surgery. We herein present a case with metastatic neuroendocrine tumor who underwent living donor liver transplantation and is surviving for 4 years.
Keywords: Neuroendocrine tumor, liver transplantation, liver tumor