Abstract
Mammography is used as a standard screening procedure for the detection of breast carcinoma in asymptomatic women . Ultrasonography (USG) and magnetic resonance (MR) are performed as alternative imaging modalities, if breast cancer may be missed at mammography. Herein a case is reported without any pathological finding on physical examination, mammography, USG and MR studies. Since there was only a family history fine-needle aspiration biopsy (FNAB) was performed and malignant epithelial cells were seen, breast carcinoma was diagnosed by this way. After infiltrative ductal carcinoma on the ground of ductal carcinoma in-situ (DCIS) was determined in the histopatologic examination of surgical biopsy specimens, modified radical mastectomy was performed. FNAB of nonpalpable breast lesions of some patients with risk and without any radiological finding must be performed or not. This question must be discussed.
Keywords:
Breast carcinoma, magnetic resonance, mammography, fine-needle aspiration biopsy
References
1Majid AS, de Paredes ES, Doherty RD, Sharma NR, Salvador X . Missed breast carcinoma: pitfalls and pearls. Radiographics, 2003;23:881-895.
2Bone B, Pentek Z, Perbeck L, et al. Diagnostic accuracy of mammography and contrast-enhanced MR imaging in 238 histologically verified breast lesions. Acta Radiologica,1997;38:489-496.
3Tilanus-Linthorst MM, Obdeijn IM, Bartels KC, et al. First experiences in screening women at high risk for breast cancer with MR imaging. Breast Cancer Res Treat, 2000;63:53-60.
4Teifke A, Hlawatsch A, Beier T, et al. Undetected malignancies of the breast: dynamic contrast- enhanced MR imaging at 1,0 T. Radiology, 2002;224:881-888.
5Hlawatsch A, Teifke A, Schmidt M, et al. Preoperative assessment of breast cancer: sonography versus MR imaging . AJR 2002;179:1493-1501.
6Gilles R, Meunier M, Trouffleau P, et al. Diagnosis of infraclinical lesions of the breast with dynamic MRI : results of a prospective and multicenter study. J Radiol, 1997;78:293-297.
7Boetes C, Strijk SP, Holland R, et al. False negative MR imaging of malignant breast tumors. Eur Radiol,1997;7:1231-1234.
8Rieber A, Merkle E, Bohm W, et al. MRI of histologically confirmed mammary carcinoma: clinical relevance of diagnostic procedures for detection of multifocal or contralateral secondary carcinoma. J Comput Assist Tomogr, 1997;21:773-779.
9Heywang–Koebrunner SH, Viehweg P, Heinig A, et al. Contrast-enhanced MRI of the breast: accuracy, value, controversies, solutions. Eur J Radiol, 1997;24:94-108.
10Miller RW, Harms S, Alvarez A . Mucinous carcinoma of the breast: potential false-negative MR imaging interpretation. AJR, 1996;167:539-540.
11De Rubeis GP, Perri S, Tavone E, et al. Non-palpable lesions of the breast : retrospective clinical study. Chir Ital, 2001;53:299-312.
12Tan SM, Behranvala KA, Trott PA, et al. A retrospective study comparing the individual modalities of triple assessment in the preoperative diagnosis of invasive lobular breast carcinoma. Eur J Surg Oncol, 2002;28:203-208.
13Pisano ED, Fajardo LL, Caudry DJ, et al. Fine-needle aspiration biopsy of nonpalpable breast lesions in a multicenter clinical trial : results from the radiologic diagnostic oncology group V. Radiology, 2001;219:785-792.
14Ustun M, Berner A, Davidson B, et al. Fine-needle aspiration cytology of lobular carcinoma in-situ. Diagn Cytopathol, 2002;27:22-26.
15Hoorntje LE, Schipper ME, Peeters PH, et al. The finding of invasive cancer after a preoperative diagnosis of ductal carcinoma in-situ: causes of ductal carcinoma in-situ underestimates with stereotactic 14-gauge needle biopsy. Ann Surg Oncol, 2003;10:748-753.
