Abstract

Prevention of intraabdominal adhesions is one of the major concerns of general surgery. The present study investigated postoperative adhesions and the effect of carboxymethylcellulose and hyaluronic acid (Seprafilm), when prosthetic materials are used for abdominal wall repairing. For this purpose, 30 rats were allocated into three groups. In each group, 2x3cm abdominal wall defect was created and repaired with prolen emesh, prolene mesh+Seprafilm and polytetrafluoroethylen emesh, respectively. All animals were sacrificed at postoperative day 7. Dense introabdominal adhesions were observed in the first and third group. In the second group, which Seprafilm is used, adhesions were significantly lower (p<0.05) than the other groups.