Abstract
Purpose: The most common anomaly seen in kidneys used for transplantation is numerical anomalies of the renal artery. The aim of our study is to discuss the artery anomalies we detected in renal transplantation cases in our clinic in line with the relevant literature.
Materials and Methods: Five (39%) of the patients were female, 8 were male (61%) and their mean age was 43.7 (22-73), mean follow- up period was 30.5 months (4 to 90). For 7 of the patients, the organs were transplanted from a cadaver and 6 were transplanted from living donors. 12 patients had double, 1 patient had three renal arteries. Six patients were given ex vivo pant type side by side reconstruction to obtain a single large artery and the external iliac was anastomosed to the artery. In 1 patient with a small inferior polar artery, the inferior polar artery was ligated. In 1 patient, the arteries were positioned by in situ anastomosis one by one. In one patient with three arteries, the upper arteries were positioned by pant type anastomosis and anastomosed as a single artery,and the lower polar artery was anastomosed with the inferior epigastric artery end to end.
Results: In four patients (30.7%) there was delayed graft function,1 patient (7.6%) developed acute rejection verified with biopsy. In the post-operative period, it was determined that 3 patients had lymphocele which did not require intervention, 1 patient had subcutaneous infection and 1 patient had perirenal hematoma. Subcutaneous infection recovered with antibiotic treatment. As for the patient with perirenal hematoma, the perirenal hematoma resorbed spontaneously.
Conclusion: Using kidneys with multiple renal arteries for transplantation brings with it some theoretical risks. Tubular necrosis, delayed graft function and rejection can be seen more frequently due to elongated cold or hot ischemia time. We are of the opinion that large and single renal artery anastomosis obtained with ex vivo pant anastomosis application can decrease the vascular complication risk in multiple renal artery.
Keywords:
Renal transplantation, multiple renal arteries, renal anomaly
References
1Shapiro R. Outcome after renal transplantation. in: Shapiro R, Simmons RL, Starzl TE. Renal Transplantation. London. Appleton Lange 1997. 1.
2Patil UD, Ragavan A, Nadaraj, et al. Helical CT angiography in evaluation of live kidney donors. Nephrol Dial Transplant 2001; 16: 1900-1904. http:// dx.doi.org/10.1093/ndt/16.9.1900 [CrossRef]
3Jonston T, Reddy K, Mastrangelo M, et al. Multiple renal arteries do not pose impediment to the routine use of laparoscopic donor nephrectomy. Clin Transplant 2001; 15: 62-65. http://dx.doi.org/10.1034/ j.1399-0012.2001.00012.x [CrossRef]
4Aki FT, Koni A, Tombul ŞT, ve ark. Çoklu renal arteri olan böbreklerle yapılan nakillerde sonuçlar, vasküler ve ürolojik komplikasyonlar. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi 2010; 19: 124-129.
5Roza AM, Perloff LJ, Naji A, et al. Livingrelated donors with bilateral multiple renal arteries. A twenty-year experience. Transplantation 1989; 47: 397-399. http://dx.doi.org/10.1097/00007890- 198902000-00045 [CrossRef]
6Oesterwitz H, Strobelt V, Scholz D, et al. Extracoprorenal microsurgical repair of injuried multiple donor kidney arteries prior of cadaveric allotransplantation. Eur Urol 1985; 11: 100-105.
7Troppman C, Viessmann K, Mc Vicar JP, et al. Incrensed transplantation of kidneys with multiple renal arteries in the laparoscopic live donor nephrectomy era: surgical technique and surgical and nonsurgical donor and recipient outcomes. Arch Surg 2001; 136: 897-907. http:// dx.doi.org/10.1001/archsurg.136.8.897 [CrossRef]
8Ozkan U, Oğuzkurt L, Tercan F, et al. Renal artery origins and variations: angiographic evaluation of 855 consecutive patients. Diagn Interv Radiol 2006; 12: 183-186.
9Kadotani Y, Okamoto M, Akioka K, et al. Management and outcome of living kidney grafts with multiple arteries. Surg Today 2005; 35: 459-466. http:// dx.doi.org/10.1007/s00595-004-2967-2 [CrossRef]
10Kumar A, Gupta RS, Srivastava A, et al. Sequential anastomosis of accessory renal artery to inferior epigastric artery in the management of multiple arteries in live related renal transplantation: a critical appraisal. Clin Transplant 2001; 15: 131-135. http://dx.doi.org/10.1034/ j.1399-0012.2001.150209.x [CrossRef]
11Emiroğlu R, Köseoğlu F, Karakayali H, et al. Multiple-artery anastomosis in kidney transplantation. Transplant Proc 2000; 32: 617-619. http://dx.doi.org/10.1016/ S0041-1345(00)00919-2 [CrossRef]
12Lippert H, Pabst R. Arterial Varitiens in Man, JF Bergmann Verlag, Munich 1985; 26-27. http://dx.doi.org/10.1007/978-3- 642-80508-0 [CrossRef]
13Makiyama K, Tanabe K, Ishida H, et al. Successful renovascular reconstruction for renal allografts with multiple renal arteries. Transplantation 2003; 75: 828-832. http://dx.doi.org/10.1097/01. TP.0000054461.57565.18 [CrossRef]
14Janschek EC, Rothe AU, Hölzenbein TJ, et al. Anatomic basis of right renal vein extension for cadaveric kidney transplantation. Urology 2004; 63: 660- 664. http://dx.doi.org/10.1016/j.urology. 2003.11.010 [CrossRef]