Abstract
Purpose: Obstructing colorectal cancer is associated with a high operative mortality and a worse prognosis. The surgical management of these patients still remains controversial. In this study, we aimed to evaluate retrospectively our approach to the patients presented to our clinic for acute mechanic intestinal obstruction caused by colorectal malignancy, and to discuss treatment results.
Material and Methods: Age, sex, physical examination findings, diagnostic methods, interval between application and operation time, operative findings and tumor localization, surgical and anastomosis technique, localization of stomas, complications, intensive care and hospital stay and mortality rates of 27 patients were recorded by searching the patients' files.
Results: Our patients consisted of 18 males and 9 females with a median age of 53 (19-90). Abdominal distention and tenderness with palpation were the most frequent physical examination findings. All patients had plain abdominal graphy while abdominopelvic ultrasonography and/or colonoscopy were used only for suitable patients. Interval between application and operation time was 36 hours (24-72 h). The most frequent tumor localization was in sigmoid colon (9 patients, %33.3) Resection with primary anastomosis was the preferred approach in 19 patients (70%). Nine (47%) of anastomosis were made by hand and 8 of them made by stapler while in 2 patients combination of two techniques were used. In 7 patients who were not suitable for resection, a diverting stoma was constructed and in one patient an ileo-colonic by-pass was the of choice. Morbidity was seen in 7 patients (3 patients with resection with primary anastomosis, 4 patients with stoma) and 7 patients (26%) died in the postoperative period. Median intensive care stay was 4 days[3 (1-4 days) days in resection with primary anastomosis patients; 5 days (3-32 days) in stoma patients] while median hospital stay was 8 days (4-32)[7 (4-28 days) days in resection with primary anastomosis patients; 11 days (6-32 days) in stoma patients].
Conclusion: Emergency resection with primary anastomosis in colorectal tumors can be performed with a low morbidity and mortality rates in selected patients.
Keywords:
Colorectal malignancy, colostomy, intestinal obstruction, primary anastomosis, surgery
References
1Midgley R, Kerr D. Colorectal cancer. Lancet 1999; 353: 391–399.
2Singh KK, Barry MK, Ralston P, et al. Audit of colorectal cancer surgery by non-specialist surgeons. Br J Surg, 1997; 84: 343–347.
3Serpell JW, McDermott FT, Katrivessis H, et al. Obstructing carcinomas of the colon. Br J Surg, 1989; 76:965–969.
4Tsugawa K, Koyanagi N, Hashizume M, et al. Therapeutic strategy of emergency surgery for colon cancer in 71 patients over 70 years of age in Japan. Hepatogastroenterology, 2002; 49: 393-398.
5Gooszen AW, Gooszen HG, Veerman W, et al. Operative treatment of acute complications of diverticular disease: primary or secondary anastomosis after sigmoid resection. Eur J Surg, 2001; 167: 35-39.
6Zorcolo L, Covotta L, Carlomagno et al. Safety of primary anastomosis in emergency colo-rectal surgery. Colorectal Dis, 2003; 5: 262-269.
7Anderson JH, Hole D, McArdle CS. Elective versus emergency surgery for patients with colorectal cancer. Br J Surg, 1992; 79: 706–709.
8Elliott TB, Yego S, Irwin TT. Five year audit of the acute complications of diverticular disease. Br J Surg, 1997; 84: 535–539.
9Seah DW, Ibrahim S, Tay KH. Hartmann procedure: is it still relevant today? ANZ J Surg, 2005; 75: 436-440.
10Meyer F, Marusch F, Koch A, et al. German Study Group “Colorectal Carcinoma (Primary Tumor)”. Emergency operation in carcinomas of the left colon: value of Hartmann's procedure. Tech Coloproctol 2004; 8 Suppl 1: 226-229.
11Polat C, Lice H, Özaçmak İD, ve ark. Komplike olmamış malign sol kolon tıkanmalarında acil rezeksiyon ve anastomozun acil rezeksiyon ve kolostomi ile karşılaştırılması. (Erken sonuçlar ve uzun vadeli sağkalım üzerine geriye dönük çalışma). Klinik ve Deneysel Cerrahi Dergisi, 2000; 8: 129-139.
12Biondo S, Jaurrieta E, Jorba R, et al. Intraoperative colonic lavage and primary anastomosis in peritonitis and obstruction. Br J Surg, 1997; 84: 222–225.
13Deen KI, Goldberg SM, Rothenburger DA. Surgical management of left colon obstruction: The University of Minnesota experience. J Am Coll Surg, 1998; 187: 573–576.
14Doğru O, Kama N, Karaayvaz M, ve ark. Kolon obstrüksiyonlarında cerrahi tedavi 162 vakalık bir inceleme. The Turkish Journal of Gastroenterology, 1991; 2: 318-325.
15Merad F, Hay JM, Fingerhut A, et al. Omentoplasty in the prevention of anastomotic leakage after colonic or rectal resection: a prospective randomized study in 712 patients. French Associations for Surgical Research. Ann Surg, 1998; 227: 179-186.
16Ahrendt GM, Tantry US, Barbul A. Intra-abdominal sepsis impairs colonic reparative collagen synthesis. Am J Surg, 1996; 171: 102-107.
17Bucher P, Gervaz P, Soravia C, et al. Randomized clinical trial of mechanical bowel preparation versus no preparation before elective left-sided colorectal surgery. Br J Surg, 2005; 92: 409–414.
18Vlot EA, Zeebregts CJ, Gerritsen JJ, et al. Anterior resection of rectal cancer without bowel preparation and diverting stoma. Surg Today, 2005; 35: 629-633.
19Forloni B, Reduzzi R, Paludetti A, et al. Intra-operative colonic lavage in emergency surgical treatment of left-sided colonic obstruction. Dis Colon Rectum, 1998; 41: 23–27.
20Polat A, Kuzu MA, Soran A, et al. Tıkayıcı kolon tümörlerinde primer rezeksiyon-anastomoz için barsak temizliği gerekli midir? Ulusal Cerrahi Dergisi, 1997; 13: 69-73.