Kavin Sugumar, Aparna Deshpande

Seth GS and King Edward Memorial Hospital, Clinic of Surgery, Mumbai, India


Objective: Chronic pancreatitis (CP) is a progressive inflammatory disorder that leads to irreversible destruction of exocrine and endocrine parenchyma. Little is known about outcomes of CP in the Indian subcontinent. We aim to study the treatment outcomes of CP in terms of pain severity in a tertiary hospital in India.

Material and Methods: This is a prospective cohort study of 75 patients diagnosed with CP. Data regarding patient demographics, symptoms, and imaging findings were recorded. Pain severity was recorded objectively by the visual analogue scale (VAS). Cambridge score was calculated, and patients were classified into mild, moderate and severe categories. Patients were treated appropriately, and pain scores were monitored at 3 months and 6 months after initial visit.

Results: Alcohol was the most common etiology (54%) followed by idiopathic/unknown causes (34%). Cambridge score or morphology on imaging did not affect pain severity (p>0.05). History of smoking and larger duct diameter decreased the effectiveness of treatment in reducing pain while higher post prandial sugar levels increased effectiveness (p<0.05). Pain relief did not differ between the treatment groups including analgesics, endoscopic or surgery (p>0.05).

Conclusion: CP presents earlier in the Indian population and represents a unique population with a greater proportion of idiopathic cases than western countries. Rather than pancreatic morphology or Cambridge score alone, a combination of morphology, pain severity and functional status can be utilized for formulating an individualized treatment plan. Present treatment strategies prove effective in treatment of CP.

Keywords: Chronic pancreatitis, pain, Cambridge score, treatment

Cite this article as: Sugumar K, Deshpande A. Outcomes of pain management in chronic pancreatitis: experience from a tertiary care hospital in India. Turk J Surg 2020; 36 (4): 359-367.


Ethics Committee Approval

The approval for this study was obtained from Seth GS Medical College and KEM Hospital Ethics Committee (Decision No: 562/16, Date: 20.06.2016).

Peer Review

Externally peer-reviewed.

Author Contributions

Concept - K.S., A.D.; Design - K.S., A.D.; Supervision - A.D.; Data Collection and/or Processing - K.S.; Analysis and/or Interpretation - K.S.; Literature Review - K.S., A.D.; Writing Manuscript - K.S., A.D.; Critical Reviews - A.D.

Conflict of Interest

All authors declare that they have no competing interests.

Financial Disclosure

No financial support was used for this study.