Colonic mucosal pseudolipomatosis: Are we aware of it?

Abstract

Objective: Colonic mucosal pseudolipomatosis is rare, and its pathogenesis is controversial. A number of mechanisms, including mechanical injury during an endoscopic procedure or chemical injury by disinfectant, seem to contribute to its pathogenesis.
Material and Methods: This retrospective study examined the colonic biopsies of 1370 patients. These biopsies were preserved at the Department of Pathology of Istanbul Training and Research Hospital between January 2012 and June 2013.
Results: We found pseudolipomatosis in 14 of 1370 colonoscopy cases (1.02%). Of these 14 patients, 8 were male and 6 were female. The male patients were between 24 and 66 years, with a mean of 39; the female patients were between 26 and 58 years, with a mean of 42.
Conclusion: Many endoscopists are unaware of the lesion, and the diagnosis is generally possible only after pathological assessment of multiple biopsies taken from suspect lesions. Here we report and discuss colonic pseudolipomatosis incidentally found in a series of patients undergoing routine colonoscopy, and we underline the endoscopic pattern and diagnostic difficulties.

Ethics committee approval was received for this study from the ethics committee of İstanbul Training and Research Hospital.

Because this is a retrospective study, we were not able to provide patient consents.

Externally peer-reviewed.

Concept - F.E., A.B.T.; Design - F.E., A.B.T., E.Ç., M.E.G.; Supervision - M.E.G., S.Ç., S.S., A.A.; Funding - E.Ç., M.E.G., S.Ç., S.S., A.A.; Materials - F.E., A.B.T., E.P., N.D.; Data Collection and/or Processing - E.Ç., M.E.G., S.Ç., S.S., A.A.; Analysis and/or Interpretation - F.E., A.B.T., E.P., N.D.; Literature Review - E.Ç., M.E.G., S.Ç., S.S., A.A.; Writer - F.E., A.B.T., E.P., N.D.; Critical Review - E.Ç., M.E.G., S.Ç., S.S., A.A., E.P., N.D.

No conflict of interest was declared by the authors.

The authors declared that this study has received no financial support.